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N-acetylcysteine amide provides neuroprotection via Nrf2-ARE pathway in a mouse model of traumatic brain injury

BACKGROUND: Increasing evidence demonstrate N-acetylcysteine amide (NACA) provides neuroprotection and attenuated oxidative stress in rats following traumatic brain injury (TBI). The nuclear factor erythroid 2-related factor 2 (Nrf2)–antioxidant response element (ARE) signal pathway is activated aft...

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Detalles Bibliográficos
Autores principales: Zhou, Yuan, Wang, Han-dong, Zhou, Xiao-ming, Fang, Jiang, Zhu, Lin, Ding, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284532/
https://www.ncbi.nlm.nih.gov/pubmed/30584276
http://dx.doi.org/10.2147/DDDT.S179227