The role of various transporters in the placental uptake of ofloxacin in an in vitro model of human villous trophoblasts

INTRODUCTION: Six years after the US Food and Drug Administration approval of the broad-spectrum antibiotic ofloxacin (OFLX), the chiral switching of this racemic mixture resulted in a drug composed of the L-optical isomer levofloxacin (LVFX). Since both fluoroquinolones (FQs) were introduced to the...

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Detalles Bibliográficos
Autores principales: Polachek, Hana, Debotton, Nir, Feinshtein, Valeria, Rubin, Mazal, Ben-Zvi, Zvi, Holcberg, Gershon, Agbaria, Riad, Dahan, Arik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284538/
https://www.ncbi.nlm.nih.gov/pubmed/30584277
http://dx.doi.org/10.2147/DDDT.S181493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284538/
https://www.ncbi.nlm.nih.gov/pubmed/30584277
http://dx.doi.org/10.2147/DDDT.S181493

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