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The role of various transporters in the placental uptake of ofloxacin in an in vitro model of human villous trophoblasts
INTRODUCTION: Six years after the US Food and Drug Administration approval of the broad-spectrum antibiotic ofloxacin (OFLX), the chiral switching of this racemic mixture resulted in a drug composed of the L-optical isomer levofloxacin (LVFX). Since both fluoroquinolones (FQs) were introduced to the...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284538/ https://www.ncbi.nlm.nih.gov/pubmed/30584277 http://dx.doi.org/10.2147/DDDT.S181493 |