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A peptide-CpG-DNA-liposome complex vaccine targeting TM4SF5 suppresses growth of pancreatic cancer in a mouse allograft model
BACKGROUND: Patients with pancreatic cancer have a poor prognosis and are usually diagnosed at a late stage. Because TM4SF5 is known to be overexpressed in hepatocellular carcinoma, colon cancer, and pancreatic cancer, it is considered as one of the candidate molecular targets for an anticancer stra...
Autores principales: | Park, Sangkyu, Kim, Dongbum, Wu, Guang, Jung, Harry, Park, Jeong-A, Kwon, Hyung-Joo, Lee, Younghee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284540/ https://www.ncbi.nlm.nih.gov/pubmed/30584324 http://dx.doi.org/10.2147/OTT.S186606 |
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