Non-neutralizing antibodies increase endogenous circulating Ang1 levels

Ang1 is a soluble ligand to receptor Tie2, and increasing the circulating Ang1 level may improve vascular stabilization under certain disease conditions. Here, we found that the circulating Ang1 level was significantly increased in cynomolgus monkeys treated with non-neutralizing anti-Ang1 antibodie...

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Detalles Bibliográficos
Autores principales: Zheng, Chao, Toth, Joshuaine, Bigwarfe, Tammy, MacDougall, Margit, Jerath, Kavita, Bovat, Kristin, Smith, James, Sun, Peng, Hayes, David, Fryer, Ryan, Singh, Sanjaya, Kroe-Barrett, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284558/
https://www.ncbi.nlm.nih.gov/pubmed/30199300
http://dx.doi.org/10.1080/19420862.2018.1521130

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