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RNA accessibility impacts potency of Tough Decoy microRNA inhibitors
MicroRNAs (miRNAs) are small RNA molecules that post-transcriptionally regulate gene expression through silencing of complementary target mRNAs. miRNAs are involved in many biological processes, including cell proliferation, differentiation, cell signaling and cellular defense responses to infection...
Autores principales: | Hooykaas, Marjolein J. G., Soppe, Jasper A., De Buhr, Hendrik M., Kruse, Elisabeth, Wiertz, Emmanuel J. H. J., Lebbink, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284568/ https://www.ncbi.nlm.nih.gov/pubmed/30339041 http://dx.doi.org/10.1080/15476286.2018.1537746 |
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