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Characterization and analysis of scFv-IgG bispecific antibody size variants

Bispecific antibodies are an emergent class of biologics that is of increasing interest for therapeutic applications. In one bispecific antibody format, single-chain variable fragments (scFv) are linked to or inserted in different locations of an intact immunoglobulin G (IgG) molecule to confer dual...

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Detalles Bibliográficos
Autores principales:	Cao, Mingyan, Wang, Chunlei, Chung, Wai Keen, Motabar, Dana, Wang, Jihong, Christian, Elizabeth, Lin, Shihua, Hunter, Alan, Wang, Xiangyang, Liu, Dengfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284595/ https://www.ncbi.nlm.nih.gov/pubmed/30130449 http://dx.doi.org/10.1080/19420862.2018.1505398

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