Cell type-specific DNA methylation in neonatal cord tissue and cord blood: a 850K-reference panel and comparison of cell types

Accounting for cellular heterogeneity is essential in neonatal epigenome-wide association studies (EWAS) performed on heterogeneous tissues, such as umbilical cord tissue (CT) or cord blood (CB). Using a reference-panel-based statistical approach, the cell type composition of heterogeneous tissues c...

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Detalles Bibliográficos
Autores principales: Lin, Xinyi, Tan, Jane Yi Lin, Teh, Ai Ling, Lim, Ives Yubin, Liew, Samantha J, MacIsaac, Julia L, Chong, Yap Seng, Gluckman, Peter D, Kobor, Michael S, Cheong, Clara Yujing, Karnani, Neerja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284779/
https://www.ncbi.nlm.nih.gov/pubmed/30232931
http://dx.doi.org/10.1080/15592294.2018.1522929

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