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Diagnosis and Treatment Algorithms of Acute Variceal Bleeding

Esophageal varices are about 10%-15% of UGIB. Over 90% of patients with cirrhosis develop portal hypertension (PHT), but not all patients with PHT and liver cirrhosis have esophageal varices. At the time of diagnosis, only 60% of patients with cirrhosis have esophageal varices. In the case of varice...

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Autores principales: BARBU, L.A., MĂRGĂRITESCU, N.D., ŞURLIN, M.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284844/
https://www.ncbi.nlm.nih.gov/pubmed/30595875
http://dx.doi.org/10.12865/CHSJ.43.03.02
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author BARBU, L.A.
MĂRGĂRITESCU, N.D.
ŞURLIN, M.V.
author_facet BARBU, L.A.
MĂRGĂRITESCU, N.D.
ŞURLIN, M.V.
author_sort BARBU, L.A.
collection PubMed
description Esophageal varices are about 10%-15% of UGIB. Over 90% of patients with cirrhosis develop portal hypertension (PHT), but not all patients with PHT and liver cirrhosis have esophageal varices. At the time of diagnosis, only 60% of patients with cirrhosis have esophageal varices. In the case of variceal bleeding suspects, vasoactive drugs should be given as soon as possible and before endoscopy. Balloon tamponade is used to obtain temporary hemostasis by direct compression of hemorrhagic varices. The variceal band ligation is already the first place in the treatment and prevention of variceal bleeding, but also in rebleeding prevention. TIPS is used as a rescue therapy after failure of drug and endoscopic therapy. The mortality assigned to the hemorrhagic episode is substantially, estimated at 13-19% of the overall mortality in hepatic cirrhosis. Current recommendations for the treatment of acute variceal bleeding are the use of combination therapy: vasoactive drugs, balloon tamponade, elastic ligation and TIPS, whose staging is done in various diagnosis and treatment algorithms.
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spelling pubmed-62848442018-12-28 Diagnosis and Treatment Algorithms of Acute Variceal Bleeding BARBU, L.A. MĂRGĂRITESCU, N.D. ŞURLIN, M.V. Curr Health Sci J Review Esophageal varices are about 10%-15% of UGIB. Over 90% of patients with cirrhosis develop portal hypertension (PHT), but not all patients with PHT and liver cirrhosis have esophageal varices. At the time of diagnosis, only 60% of patients with cirrhosis have esophageal varices. In the case of variceal bleeding suspects, vasoactive drugs should be given as soon as possible and before endoscopy. Balloon tamponade is used to obtain temporary hemostasis by direct compression of hemorrhagic varices. The variceal band ligation is already the first place in the treatment and prevention of variceal bleeding, but also in rebleeding prevention. TIPS is used as a rescue therapy after failure of drug and endoscopic therapy. The mortality assigned to the hemorrhagic episode is substantially, estimated at 13-19% of the overall mortality in hepatic cirrhosis. Current recommendations for the treatment of acute variceal bleeding are the use of combination therapy: vasoactive drugs, balloon tamponade, elastic ligation and TIPS, whose staging is done in various diagnosis and treatment algorithms. Medical University Publishing House Craiova 2017 2017-09-28 /pmc/articles/PMC6284844/ /pubmed/30595875 http://dx.doi.org/10.12865/CHSJ.43.03.02 Text en Copyright © 2017, Medical University Publishing House Craiova http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Review
BARBU, L.A.
MĂRGĂRITESCU, N.D.
ŞURLIN, M.V.
Diagnosis and Treatment Algorithms of Acute Variceal Bleeding
title Diagnosis and Treatment Algorithms of Acute Variceal Bleeding
title_full Diagnosis and Treatment Algorithms of Acute Variceal Bleeding
title_fullStr Diagnosis and Treatment Algorithms of Acute Variceal Bleeding
title_full_unstemmed Diagnosis and Treatment Algorithms of Acute Variceal Bleeding
title_short Diagnosis and Treatment Algorithms of Acute Variceal Bleeding
title_sort diagnosis and treatment algorithms of acute variceal bleeding
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284844/
https://www.ncbi.nlm.nih.gov/pubmed/30595875
http://dx.doi.org/10.12865/CHSJ.43.03.02
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