Therapeutic Options in Diffuse Large B-Cell Lymphoma - A Retrospective Study and Review of the Literature

The aim of this retrospective study was to assess the differences between standard R-CHOP and other Rituximab-associated chemotherapy (R-miniCHOP and R-CHOEP) regimens in terms of survival and potential adverse effects. The six-month survival outcomes of 94 diffuse large B-cell lymphomas (DLBCL) pat...

Descripción completa

Detalles Bibliográficos
Autores principales: PATRASCU, ANA-MARIA, NACEA, JANINA, PATRASCU, Ş., GOGANAU, A., DELCEA, FLORENTINA, MOGOANTA, L., ROTARU, IONELA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284846/
https://www.ncbi.nlm.nih.gov/pubmed/30595888
http://dx.doi.org/10.12865/CHSJ.43.03.15
Descripción
Sumario:The aim of this retrospective study was to assess the differences between standard R-CHOP and other Rituximab-associated chemotherapy (R-miniCHOP and R-CHOEP) regimens in terms of survival and potential adverse effects. The six-month survival outcomes of 94 diffuse large B-cell lymphomas (DLBCL) patients indicated no statistical difference between overall survival and disease-free survival in the two subgroups. The biological response to therapy (blood count, LDH levels) was similar in both subgroups. Despite having different clinical indications, R-miniCHOP and R-CHOEP provide viable therapeutic alternatives to the standard R-CHOP regimen.

Ejemplares similares