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PathFX provides mechanistic insights into drug efficacy and safety for regulatory review and therapeutic development

Failure to demonstrate efficacy and safety issues are important reasons that drugs do not reach the market. An incomplete understanding of how drugs exert their effects hinders regulatory and pharmaceutical industry projections of a drug’s benefits and risks. Signaling pathways mediate drug response...

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Detalles Bibliográficos
Autores principales: Wilson, Jennifer L., Racz, Rebecca, Liu, Tianyun, Adeniyi, Oluseyi, Sun, Jielin, Ramamoorthy, Anuradha, Pacanowski, Michael, Altman, Russ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285459/
https://www.ncbi.nlm.nih.gov/pubmed/30532240
http://dx.doi.org/10.1371/journal.pcbi.1006614