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PathFX provides mechanistic insights into drug efficacy and safety for regulatory review and therapeutic development
Failure to demonstrate efficacy and safety issues are important reasons that drugs do not reach the market. An incomplete understanding of how drugs exert their effects hinders regulatory and pharmaceutical industry projections of a drug’s benefits and risks. Signaling pathways mediate drug response...
Autores principales: | Wilson, Jennifer L., Racz, Rebecca, Liu, Tianyun, Adeniyi, Oluseyi, Sun, Jielin, Ramamoorthy, Anuradha, Pacanowski, Michael, Altman, Russ |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285459/ https://www.ncbi.nlm.nih.gov/pubmed/30532240 http://dx.doi.org/10.1371/journal.pcbi.1006614 |
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