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Thiazide-associated hyponatremia attenuates the fracture-protective effect of thiazide: A population-based study

BACKGROUND: Thiazide, a first-line therapy for hypertension, lowers blood pressure, increases bone mineral density, and reduces the risk of fractures. However, hyponatremia, an adverse effect of thiazide, is associated with increased risk of osteoporosis and fractures. It is currently unclear whethe...

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Detalles Bibliográficos
Autores principales: Yang, Lii-Jia, Wu, Ping-Hsun, Huang, Teng-Hui, Lin, Ming-Yen, Tsai, Jer-Chia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285977/
https://www.ncbi.nlm.nih.gov/pubmed/30532245
http://dx.doi.org/10.1371/journal.pone.0208712