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Thiazide-associated hyponatremia attenuates the fracture-protective effect of thiazide: A population-based study
BACKGROUND: Thiazide, a first-line therapy for hypertension, lowers blood pressure, increases bone mineral density, and reduces the risk of fractures. However, hyponatremia, an adverse effect of thiazide, is associated with increased risk of osteoporosis and fractures. It is currently unclear whethe...
Autores principales: | Yang, Lii-Jia, Wu, Ping-Hsun, Huang, Teng-Hui, Lin, Ming-Yen, Tsai, Jer-Chia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285977/ https://www.ncbi.nlm.nih.gov/pubmed/30532245 http://dx.doi.org/10.1371/journal.pone.0208712 |
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