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Characterizing changes in glucocorticoid receptor internalization in the fear circuit in an animal model of post traumatic stress disorder
Glucocorticoid receptors (GRs) shuttle from the cytoplasm (cy) to the nucleus (nu) when bound with glucocorticoids (i.e. GR internalization) and alter transcriptional activity. GR activation within the fear circuit has been implicated in fear memory and post traumatic stress disorder (PTSD). However...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286002/ https://www.ncbi.nlm.nih.gov/pubmed/30532228 http://dx.doi.org/10.1371/journal.pone.0205144 |