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Treatment with XAV-939 prevents in vitro calcification of human valvular interstitial cells
The development of a substance or inhibitor-based treatment strategy for the prevention of aortic valve stenosis is a challenge and a main focus of medical research in this area. One strategy may be to use the tankyrase inhibitor XAV-939, which leads to Axin stabilisation and subsequent destruction...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286025/ https://www.ncbi.nlm.nih.gov/pubmed/30532256 http://dx.doi.org/10.1371/journal.pone.0208774 |