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Treatment with XAV-939 prevents in vitro calcification of human valvular interstitial cells

The development of a substance or inhibitor-based treatment strategy for the prevention of aortic valve stenosis is a challenge and a main focus of medical research in this area. One strategy may be to use the tankyrase inhibitor XAV-939, which leads to Axin stabilisation and subsequent destruction...

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Detalles Bibliográficos
Autores principales:	Dittfeld, Claudia, Reimann, Gabriel, Mieting, Alice, Büttner, Petra, Jannasch, Anett, Plötze, Katrin, Steiner, Gerald, Tugtekin, Sems Malte, Matschke, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286025/ https://www.ncbi.nlm.nih.gov/pubmed/30532256 http://dx.doi.org/10.1371/journal.pone.0208774

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