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Fluconazole induces ROS in Cryptococcus neoformans and contributes to DNA damage in vitro

Pathogenic basidiomycetous yeast, Cryptococcus neoformans, causes fatal meningitis in immunocompromised individuals. Fluconazole (FLC) is a fungistatic drug commonly administered to treat cryptococcosis. Unfortunately, FLC-resistant strains characterized by various degree of chromosomal instability...

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Detalles Bibliográficos
Autores principales:	Peng, Congyue Annie, Gaertner, Andrea A. E., Henriquez, Sarah Ana, Fang, Diana, Colon-Reyes, Rodney J., Brumaghim, Julia L., Kozubowski, Lukasz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286144/ https://www.ncbi.nlm.nih.gov/pubmed/30532246 http://dx.doi.org/10.1371/journal.pone.0208471

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