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A screening campaign in sea urchin egg homogenate as a platform for discovering modulators of NAADP-dependent Ca(2+) signaling in human cells
The Ca(2+) mobilizing second messenger nicotinic acid adenine dinucleotide phosphate (NAADP) regulates intracellular trafficking events, including translocation of certain enveloped viruses through the endolysosomal system. Targeting NAADP-evoked Ca(2+) signaling may therefore be an effective strate...
Autores principales: | Gunaratne, Gihan S., Johns, Malcolm E., Hintz, Hallie M., Walseth, Timothy F., Marchant, Jonathan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286156/ https://www.ncbi.nlm.nih.gov/pubmed/30145428 http://dx.doi.org/10.1016/j.ceca.2018.08.002 |
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