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A screening campaign in sea urchin egg homogenate as a platform for discovering modulators of NAADP-dependent Ca(2+) signaling in human cells

The Ca(2+) mobilizing second messenger nicotinic acid adenine dinucleotide phosphate (NAADP) regulates intracellular trafficking events, including translocation of certain enveloped viruses through the endolysosomal system. Targeting NAADP-evoked Ca(2+) signaling may therefore be an effective strate...

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Detalles Bibliográficos
Autores principales: Gunaratne, Gihan S., Johns, Malcolm E., Hintz, Hallie M., Walseth, Timothy F., Marchant, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286156/
https://www.ncbi.nlm.nih.gov/pubmed/30145428
http://dx.doi.org/10.1016/j.ceca.2018.08.002

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