T cell-derived lymphotoxin limits Th1 response during HSV-1 infection

Though lymphotoxin (LT) is highly expressed by type I helper T (Th1) cells, its contribution to CD4(+) T cell differentiation during infections and diseases remains a mystery. In HSV-1 infection, we observed that LTβR signaling is required to limit the Th1 response. Using bone marrow chimeric mice,...

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Detalles Bibliográficos
Autores principales: Yang, Kaiting, Liang, Yong, Sun, Zhichen, Liu, Longchao, Liao, Jing, Xu, Hairong, Zhu, Mingzhao, Fu, Yang-Xin, Peng, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286317/
https://www.ncbi.nlm.nih.gov/pubmed/30531962
http://dx.doi.org/10.1038/s41598-018-36012-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286317/
https://www.ncbi.nlm.nih.gov/pubmed/30531962
http://dx.doi.org/10.1038/s41598-018-36012-z

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