Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates

Antimicrobial peptides (AMPs) constitute promising alternatives to classical antibiotics for the treatment of drug-resistant infections, which are a rapidly emerging global health challenge. However, our understanding of the structure-function relationships of AMPs is limited, and we are just beginn...

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Detalles Bibliográficos
Autores principales: Torres, Marcelo D. T., Pedron, Cibele N., Higashikuni, Yasutomi, Kramer, Robin M., Cardoso, Marlon H., Oshiro, Karen G. N., Franco, Octávio L., Silva Junior, Pedro I., Silva, Fernanda D., Oliveira Junior, Vani X., Lu, Timothy K., de la Fuente-Nunez, Cesar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286318/
https://www.ncbi.nlm.nih.gov/pubmed/30534613
http://dx.doi.org/10.1038/s42003-018-0224-2

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