PDL2(+) CD11b(+) dermal dendritic cells capture topical antigen through hair follicles to prime LAP(+) Tregs

The skin immune system must discriminate between innocuous antigens and pathogens. Antigen applied topically using a Viaskin® patch elicits immune tolerance that can suppress colitis and food allergy. Here we show how topical antigen is acquired and presented by dendritic cells in the skin. Topical...

Descripción completa

Detalles Bibliográficos
Autores principales: Tordesillas, Leticia, Lozano-Ojalvo, Daniel, Dunkin, David, Mondoulet, Lucie, Agudo, Judith, Merad, Miriam, Sampson, Hugh A., Berin, M. Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286332/
https://www.ncbi.nlm.nih.gov/pubmed/30531969
http://dx.doi.org/10.1038/s41467-018-07716-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286332/
https://www.ncbi.nlm.nih.gov/pubmed/30531969
http://dx.doi.org/10.1038/s41467-018-07716-7

Ejemplares similares