Safety evaluation of frequent application of microbubble-enhanced focused ultrasound blood-brain-barrier opening

Focused ultrasound (FUS) with the presence of microbubbles induces blood brain barrier (BBB) opening in targeted areas and facilitates drug delivery. However, recent studies have indicated that FUS-BBB opening with excessive exposure levels may be associated with inflammatory response and cellular/t...

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Detalles Bibliográficos
Autores principales: Tsai, Hong-Chieh, Tsai, Chih-Hung, Chen, Wen-Shiang, Inserra, Claude, Wei, Kuo-Chen, Liu, Hao-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286368/
https://www.ncbi.nlm.nih.gov/pubmed/30531863
http://dx.doi.org/10.1038/s41598-018-35677-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286368/
https://www.ncbi.nlm.nih.gov/pubmed/30531863
http://dx.doi.org/10.1038/s41598-018-35677-w

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