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Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors

microRNAs are key regulators of the human transcriptome across a number of diverse biological processes, such as development, aging and cancer, where particular miRNAs have been identified as tumour suppressive and oncogenic. In this work, we elucidate, in a comprehensive manner, across 15 epithelia...

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Detalles Bibliográficos
Autores principales: Dhawan, Andrew, Scott, Jacob G., Harris, Adrian L., Buffa, Francesca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286392/
https://www.ncbi.nlm.nih.gov/pubmed/30531873
http://dx.doi.org/10.1038/s41467-018-07657-1