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Effect of oxygen supplementation on propofol anesthesia in acepromazine/tramadol premedicated dogs

Research in the area of injectable anesthetics in dogs requires mindfulness of ventilation, in order to supply artificial oxygen, which is often achieved with special equipment which may be unaffordable for veterinarians in developing countries. This study evaluated the effect of oxygen supplementat...

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Autores principales: Bolaji-Alabi, Foluso B., Solanke, Oladipo I., Adetunji, Adeniran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty of Veterinary Medicine, Cairo University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286402/
https://www.ncbi.nlm.nih.gov/pubmed/30564602
http://dx.doi.org/10.1016/j.ijvsm.2018.08.005
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author Bolaji-Alabi, Foluso B.
Solanke, Oladipo I.
Adetunji, Adeniran
author_facet Bolaji-Alabi, Foluso B.
Solanke, Oladipo I.
Adetunji, Adeniran
author_sort Bolaji-Alabi, Foluso B.
collection PubMed
description Research in the area of injectable anesthetics in dogs requires mindfulness of ventilation, in order to supply artificial oxygen, which is often achieved with special equipment which may be unaffordable for veterinarians in developing countries. This study evaluated the effect of oxygen supplementation in dogs anesthetized with acepromazine-tramadol-propofol. Six Nigerian indigenous dogs were premedicated with intramuscular injection of acepromazine (0.03 mg/kg) and tramadol (5 mg/kg), followed by induction of anesthesia with propofol (4 mg/kg) IV 20 min later. Maintenance of anesthesia for 2 h was achieved with repeated bolus injections of propofol (2 mg/kg) at 10 min interval and anesthetized dogs breathed oxygen. This experimental trial was repeated a week later without oxygen supply as a control. Anesthetic indices, cardiopulmonary parameters, and rectal temperature were recorded at 10 min intervals for 2 h. Duration of anesthesia, duration of recumbency, time to extubation, and time to standing were not significantly (P > .05) different from their respective control values. Mean heart rate progressively decreased from the 60 min interval in both groups of anesthetized dogs. Mean arterial pressure in dogs with supplemented oxygen was similar to the control group. The mean oxygen-haemoglobin saturation was similar in both experimental trials. There was a progressive decrease in rectal temperature from the 60 min interval in both groups of anesthetized dogs. It was concluded that bolus injection of propofol, with and without supplemental oxygen, appeared to be efficacious and relatively safe in acepromazine-tramadol premedicated healthy dogs not undergoing any surgical or diagnostic procedures.
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spelling pubmed-62864022018-12-18 Effect of oxygen supplementation on propofol anesthesia in acepromazine/tramadol premedicated dogs Bolaji-Alabi, Foluso B. Solanke, Oladipo I. Adetunji, Adeniran Int J Vet Sci Med Original Research Article Research in the area of injectable anesthetics in dogs requires mindfulness of ventilation, in order to supply artificial oxygen, which is often achieved with special equipment which may be unaffordable for veterinarians in developing countries. This study evaluated the effect of oxygen supplementation in dogs anesthetized with acepromazine-tramadol-propofol. Six Nigerian indigenous dogs were premedicated with intramuscular injection of acepromazine (0.03 mg/kg) and tramadol (5 mg/kg), followed by induction of anesthesia with propofol (4 mg/kg) IV 20 min later. Maintenance of anesthesia for 2 h was achieved with repeated bolus injections of propofol (2 mg/kg) at 10 min interval and anesthetized dogs breathed oxygen. This experimental trial was repeated a week later without oxygen supply as a control. Anesthetic indices, cardiopulmonary parameters, and rectal temperature were recorded at 10 min intervals for 2 h. Duration of anesthesia, duration of recumbency, time to extubation, and time to standing were not significantly (P > .05) different from their respective control values. Mean heart rate progressively decreased from the 60 min interval in both groups of anesthetized dogs. Mean arterial pressure in dogs with supplemented oxygen was similar to the control group. The mean oxygen-haemoglobin saturation was similar in both experimental trials. There was a progressive decrease in rectal temperature from the 60 min interval in both groups of anesthetized dogs. It was concluded that bolus injection of propofol, with and without supplemental oxygen, appeared to be efficacious and relatively safe in acepromazine-tramadol premedicated healthy dogs not undergoing any surgical or diagnostic procedures. Faculty of Veterinary Medicine, Cairo University 2018-08-28 /pmc/articles/PMC6286402/ /pubmed/30564602 http://dx.doi.org/10.1016/j.ijvsm.2018.08.005 Text en © 2018 Faculty of Veterinary Medicine, Cairo University. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research Article
Bolaji-Alabi, Foluso B.
Solanke, Oladipo I.
Adetunji, Adeniran
Effect of oxygen supplementation on propofol anesthesia in acepromazine/tramadol premedicated dogs
title Effect of oxygen supplementation on propofol anesthesia in acepromazine/tramadol premedicated dogs
title_full Effect of oxygen supplementation on propofol anesthesia in acepromazine/tramadol premedicated dogs
title_fullStr Effect of oxygen supplementation on propofol anesthesia in acepromazine/tramadol premedicated dogs
title_full_unstemmed Effect of oxygen supplementation on propofol anesthesia in acepromazine/tramadol premedicated dogs
title_short Effect of oxygen supplementation on propofol anesthesia in acepromazine/tramadol premedicated dogs
title_sort effect of oxygen supplementation on propofol anesthesia in acepromazine/tramadol premedicated dogs
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286402/
https://www.ncbi.nlm.nih.gov/pubmed/30564602
http://dx.doi.org/10.1016/j.ijvsm.2018.08.005
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