Cargando…

Association of Some Components of the Metabolic Syndrome with the Subtype of Mild Cognitive Impairment

ABSTRACT: In the last 30 years there has been a long way in what concerns the ability to test and diagnose cognitive disorders. On the other hand, it is more and more obvious the necessity to discover new parameters, which can clearly witness the passage from the physiological state of aging to a co...

Descripción completa

Detalles Bibliográficos
Autores principales: COTEANU, CATALINA, GUSTI, ALICE, COTEANU, M.F., GUSTI, SIMONA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286459/
https://www.ncbi.nlm.nih.gov/pubmed/30595902
http://dx.doi.org/10.12865/CHSJ.43.04.11
_version_ 1783379456816054272
author COTEANU, CATALINA
GUSTI, ALICE
COTEANU, M.F.
GUSTI, SIMONA
author_facet COTEANU, CATALINA
GUSTI, ALICE
COTEANU, M.F.
GUSTI, SIMONA
author_sort COTEANU, CATALINA
collection PubMed
description ABSTRACT: In the last 30 years there has been a long way in what concerns the ability to test and diagnose cognitive disorders. On the other hand, it is more and more obvious the necessity to discover new parameters, which can clearly witness the passage from the physiological state of aging to a cognitive impairment in various stages (ranging from mild cognitive impairment to severe dementia). Bringing together all the clinical, paraclinical and neuropsychological data trying to discover the missing link between metabolic disorders, chronic inflammatory changes, progression of atherosclerosis, and the appearance of cognitive disorders, remains an extremely attractive and challenging field of research. By this study, we observed that there is a slight supremacy of the amnestic-MCI in patients with metabolic syndrome, without being able to extract statistically significant data. The interesting data obtained in this study emphasized the connection between the triglycerides/HDL-cholesterol ratio and the presence of the amnestic-MCI subtypes in patients with metabolic syndrome. The data obtained led to the conclusion that an increase in diastolic blood pressure in older people is a prediction factor for cognitive decline.
format Online
Article
Text
id pubmed-6286459
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Medical University Publishing House Craiova
record_format MEDLINE/PubMed
spelling pubmed-62864592018-12-28 Association of Some Components of the Metabolic Syndrome with the Subtype of Mild Cognitive Impairment COTEANU, CATALINA GUSTI, ALICE COTEANU, M.F. GUSTI, SIMONA Curr Health Sci J Original Paper ABSTRACT: In the last 30 years there has been a long way in what concerns the ability to test and diagnose cognitive disorders. On the other hand, it is more and more obvious the necessity to discover new parameters, which can clearly witness the passage from the physiological state of aging to a cognitive impairment in various stages (ranging from mild cognitive impairment to severe dementia). Bringing together all the clinical, paraclinical and neuropsychological data trying to discover the missing link between metabolic disorders, chronic inflammatory changes, progression of atherosclerosis, and the appearance of cognitive disorders, remains an extremely attractive and challenging field of research. By this study, we observed that there is a slight supremacy of the amnestic-MCI in patients with metabolic syndrome, without being able to extract statistically significant data. The interesting data obtained in this study emphasized the connection between the triglycerides/HDL-cholesterol ratio and the presence of the amnestic-MCI subtypes in patients with metabolic syndrome. The data obtained led to the conclusion that an increase in diastolic blood pressure in older people is a prediction factor for cognitive decline. Medical University Publishing House Craiova 2017 2017-12-28 /pmc/articles/PMC6286459/ /pubmed/30595902 http://dx.doi.org/10.12865/CHSJ.43.04.11 Text en Copyright © 2017, Medical University Publishing House Craiova http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Original Paper
COTEANU, CATALINA
GUSTI, ALICE
COTEANU, M.F.
GUSTI, SIMONA
Association of Some Components of the Metabolic Syndrome with the Subtype of Mild Cognitive Impairment
title Association of Some Components of the Metabolic Syndrome with the Subtype of Mild Cognitive Impairment
title_full Association of Some Components of the Metabolic Syndrome with the Subtype of Mild Cognitive Impairment
title_fullStr Association of Some Components of the Metabolic Syndrome with the Subtype of Mild Cognitive Impairment
title_full_unstemmed Association of Some Components of the Metabolic Syndrome with the Subtype of Mild Cognitive Impairment
title_short Association of Some Components of the Metabolic Syndrome with the Subtype of Mild Cognitive Impairment
title_sort association of some components of the metabolic syndrome with the subtype of mild cognitive impairment
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286459/
https://www.ncbi.nlm.nih.gov/pubmed/30595902
http://dx.doi.org/10.12865/CHSJ.43.04.11
work_keys_str_mv AT coteanucatalina associationofsomecomponentsofthemetabolicsyndromewiththesubtypeofmildcognitiveimpairment
AT gustialice associationofsomecomponentsofthemetabolicsyndromewiththesubtypeofmildcognitiveimpairment
AT coteanumf associationofsomecomponentsofthemetabolicsyndromewiththesubtypeofmildcognitiveimpairment
AT gustisimona associationofsomecomponentsofthemetabolicsyndromewiththesubtypeofmildcognitiveimpairment