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A high-fat diet alters genome-wide DNA methylation and gene expression in SM/J mice

BACKGROUND: While the genetics of obesity has been well defined, the epigenetics of obesity is poorly understood. Here, we used a genome-wide approach to identify genes with differences in both DNA methylation and expression associated with a high-fat diet in mice. RESULTS: We weaned genetically ide...

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Detalles Bibliográficos
Autores principales:	Keleher, Madeline Rose, Zaidi, Rabab, Hicks, Lauren, Shah, Shyam, Xing, Xiaoyun, Li, Daofeng, Wang, Ting, Cheverud, James M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286549/ https://www.ncbi.nlm.nih.gov/pubmed/30526554 http://dx.doi.org/10.1186/s12864-018-5327-0

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