OPCML is hypermethylated in a subset of patients with metaplastic changes in their esophagus

OPCML hypermethylation is considered a promising cancer biomarker. We examined methylation levels in the first exon of OPCML in two patient cohorts within the esophageal adenocarcinoma and gastric adenocarcinoma cascades and in a range of cell-lines using a custom PyroMark CpG assay. Methylation lev...

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Detalles Bibliográficos
Autores principales: Castaño-Rodríguez, Natalia, Popple, Georgia L., Porras-Hurtado, Gloria Liliana, Cardona-Deazza, José Luis, Montoya-Martinez, Juan José, Cadavid-Velez, Antonio Javier, Toro-Hidalgo, Héctor William, Cobo-Alvarado, Alba Ruth, del Socorro Hincapié-Rincón, Ofelia, Riordan, Stephen M., Kaakoush, Nadeem O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286609/
https://www.ncbi.nlm.nih.gov/pubmed/30555700
http://dx.doi.org/10.1186/s40364-018-0150-y

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