The orphan nuclear receptor EAR-2 (NR2F6) inhibits hematopoietic cell differentiation and induces myeloid dysplasia in vivo

BACKGROUND: In patients with myelodysplastic syndrome (MDS), bone marrow cells have an increased predisposition to apoptosis, yet MDS cells outcompete normal bone marrow (BM)-- suggesting that factors regulating growth potential may be important in MDS. We previously identified v-Erb A related-2 (EA...

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Detalles Bibliográficos
Autores principales: Ichim, Christine V., Dervovic, Dzana D., Chan, Lap Shu Alan, Robertson, Claire J., Chesney, Alden, Reis, Marciano D., Wells, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286615/
https://www.ncbi.nlm.nih.gov/pubmed/30555701
http://dx.doi.org/10.1186/s40364-018-0149-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286615/
https://www.ncbi.nlm.nih.gov/pubmed/30555701
http://dx.doi.org/10.1186/s40364-018-0149-4

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