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Long noncoding RNA PCAT6 functions as an oncogene by binding to EZH2 and suppressing LATS2 in non-small-cell lung cancer

BACKGROUND: NSCLC (non-small-cell lung cancer) is the leading cause of cancer-related mortality worldwide. Both epigenetic and genetic changes contribute to the initiation, development and metastasis of NSCLC. Recently, accumulating data have begun to support the notion that long noncoding RNAs (lnc...

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Detalles Bibliográficos
Autores principales: Shi, Xuefei, Liu, Zhili, Liu, Zhicong, Feng, Xueren, Hua, Feng, Hu, Xixian, Wang, Bin, Lu, Kaihua, Nie, Fengqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286630/
https://www.ncbi.nlm.nih.gov/pubmed/30314898
http://dx.doi.org/10.1016/j.ebiom.2018.10.004