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Noncanonical farnesoid X receptor signaling inhibits apoptosis and impedes liver fibrosis
BACKGROUND: Hepatocyte is particularly vulnerable to apoptosis, a hallmark of many liver diseases. Although pro-apoptotic mechanisms have been extensively explored, less is known about the hepatocyte-specific anti-apoptotic molecular events and it lacks effective approach to combat hepatocyte apopto...
Autores principales: | Wang, Hong, Ge, Chaoliang, Zhou, Jiyu, Guo, Yitong, Cui, Shuang, Huang, Ningning, Yan, Tingting, Cao, Lijuan, Che, Yuan, Zheng, Qiuling, Zheng, Xiao, Gonzalez, Frank J., Wang, Guangji, Hao, Haiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286639/ https://www.ncbi.nlm.nih.gov/pubmed/30337250 http://dx.doi.org/10.1016/j.ebiom.2018.10.028 |
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