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Day-Night Oscillation of Atrogin1 and Timing-Dependent Preventive Effect of Weight-Bearing on Muscle Atrophy
BACKGROUND: Atrogin1, which is one of the key genes for the promotion of muscle atrophy, exhibits day-night variation. However, its mechanism and the role of its day-night variation are largely unknown in a muscle atrophic context. METHODS: The mice were induced a muscle atrophy by hindlimb-unloadin...
Autores principales: | Aoyama, Shinya, Kojima, Shuichi, Sasaki, Keisuke, Ishikawa, Ryosuke, Tanaka, Mizuho, Shimoda, Takeru, Hattori, Yuta, Aoki, Natsumi, Takahashi, Kengo, Hirooka, Rina, Takizawa, Miku, Haraguchi, Atsushi, Shibata, Shigenobu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286653/ https://www.ncbi.nlm.nih.gov/pubmed/30391495 http://dx.doi.org/10.1016/j.ebiom.2018.10.057 |
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