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Regulation of invariant NKT cell development and function by a 0.14 Mbp locus on chromosome 1: a possible role for Fcgr3

Invariant NKT (iNKT) cells are tissue-resident innate-like T cells critical to the host immune response. We previously identified a 6.6 Mbp region on chromosome 1 as a major regulator of iNKT cell number and function in C57BL/6 and 129X1/SvJ mice. Here, we fine-mapped this locus by assessing the iNK...

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Detalles Bibliográficos
Autores principales:	DeVault, Victoria L., Malagic, Murisa, Mei, Linda, Dienz, Oliver, Lilley, Graham W. J., Benoit, Patrick, Mistri, Somen K., Musial, Shawn C., Ather, Jennifer L., Poynter, Matthew E., Boyson, Jonathan E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286708/ https://www.ncbi.nlm.nih.gov/pubmed/29880961 http://dx.doi.org/10.1038/s41435-018-0031-2

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