Sleep and Memory Disorders in a Patient Suffering from Charcot-Marie-Tooth Disease

Currently incurable, Charcot-Marie-Tooth (CMT) disease is the most commonly inherited neurological disorder, which affects a small percentage of the population. The most common cause of CMT is the duplication of a region on the short arm of chromosome 17, which includes the gene PMP22. We report a t...

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Autores principales: FLORESCU, C., ALBU, C.V., DUMITRESCU, C., TÂRTEA, G.C., FLORESCU, O.A., TÂRTEA, E.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286719/
https://www.ncbi.nlm.nih.gov/pubmed/30595858
http://dx.doi.org/10.12865/CHSJ.43.01.11
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author FLORESCU, C.
ALBU, C.V.
DUMITRESCU, C.
TÂRTEA, G.C.
FLORESCU, O.A.
TÂRTEA, E.A.
author_facet FLORESCU, C.
ALBU, C.V.
DUMITRESCU, C.
TÂRTEA, G.C.
FLORESCU, O.A.
TÂRTEA, E.A.
author_sort FLORESCU, C.
collection PubMed
description Currently incurable, Charcot-Marie-Tooth (CMT) disease is the most commonly inherited neurological disorder, which affects a small percentage of the population. The most common cause of CMT is the duplication of a region on the short arm of chromosome 17, which includes the gene PMP22. We report a thirty-seven-year-old man with CMT disease having sleep, memory and attention disorders characterized by brief retrograde amnesia at early age. The patient has no genetic disease in the family, but was diagnosed with diabetes mellitus, which emphasizes the sensory loss and prolonged infections. Diabetes mellitus emphasizes the sensory symptomatology and predisposes to the development of infections with delayed healing.
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spelling pubmed-62867192018-12-28 Sleep and Memory Disorders in a Patient Suffering from Charcot-Marie-Tooth Disease FLORESCU, C. ALBU, C.V. DUMITRESCU, C. TÂRTEA, G.C. FLORESCU, O.A. TÂRTEA, E.A. Curr Health Sci J Case Report Currently incurable, Charcot-Marie-Tooth (CMT) disease is the most commonly inherited neurological disorder, which affects a small percentage of the population. The most common cause of CMT is the duplication of a region on the short arm of chromosome 17, which includes the gene PMP22. We report a thirty-seven-year-old man with CMT disease having sleep, memory and attention disorders characterized by brief retrograde amnesia at early age. The patient has no genetic disease in the family, but was diagnosed with diabetes mellitus, which emphasizes the sensory loss and prolonged infections. Diabetes mellitus emphasizes the sensory symptomatology and predisposes to the development of infections with delayed healing. Medical University Publishing House Craiova 2017 2017-09-27 /pmc/articles/PMC6286719/ /pubmed/30595858 http://dx.doi.org/10.12865/CHSJ.43.01.11 Text en Copyright © 2017, Medical University Publishing House Craiova http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Case Report
FLORESCU, C.
ALBU, C.V.
DUMITRESCU, C.
TÂRTEA, G.C.
FLORESCU, O.A.
TÂRTEA, E.A.
Sleep and Memory Disorders in a Patient Suffering from Charcot-Marie-Tooth Disease
title Sleep and Memory Disorders in a Patient Suffering from Charcot-Marie-Tooth Disease
title_full Sleep and Memory Disorders in a Patient Suffering from Charcot-Marie-Tooth Disease
title_fullStr Sleep and Memory Disorders in a Patient Suffering from Charcot-Marie-Tooth Disease
title_full_unstemmed Sleep and Memory Disorders in a Patient Suffering from Charcot-Marie-Tooth Disease
title_short Sleep and Memory Disorders in a Patient Suffering from Charcot-Marie-Tooth Disease
title_sort sleep and memory disorders in a patient suffering from charcot-marie-tooth disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286719/
https://www.ncbi.nlm.nih.gov/pubmed/30595858
http://dx.doi.org/10.12865/CHSJ.43.01.11
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