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Early Stone Manipulation in Urinary Tract Infection Associated with Obstructing Nephrolithiasis

A urinary tract infection (UTI) and sepsis secondary to an obstructing stone are one of the few true urological emergencies. The accepted management of infected ureteral stones includes emergent decompression of the collecting system as well as antibiotic therapy. Despite this, no consensus guidelin...

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Autores principales: Swonke, Megan L., Mahmoud, Ali M., Farran, Elias J., Dafashy, Tamer J., Kerr, Preston S., Kosarek, Christopher D., Sonstein, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286750/
https://www.ncbi.nlm.nih.gov/pubmed/30595937
http://dx.doi.org/10.1155/2018/2303492
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author Swonke, Megan L.
Mahmoud, Ali M.
Farran, Elias J.
Dafashy, Tamer J.
Kerr, Preston S.
Kosarek, Christopher D.
Sonstein, Joseph
author_facet Swonke, Megan L.
Mahmoud, Ali M.
Farran, Elias J.
Dafashy, Tamer J.
Kerr, Preston S.
Kosarek, Christopher D.
Sonstein, Joseph
author_sort Swonke, Megan L.
collection PubMed
description A urinary tract infection (UTI) and sepsis secondary to an obstructing stone are one of the few true urological emergencies. The accepted management of infected ureteral stones includes emergent decompression of the collecting system as well as antibiotic therapy. Despite this, no consensus guidelines clarify the optimal time to undergo definitive stone management following decompression. Historically, our institution has performed ureteroscopy with laser lithotripsy (URS-LL) treatment at least 1 to 2 weeks after decompression to allow for clinical improvement and completion of an antibiotic course. In this case series, we retrospectively review four cases in which patients had a documented UTI secondary to an obstructive ureteral stone. The patients underwent urgent decompression and, based on labs and clinical improvement, were subsequently treated with URS-LL. The presented patients received URS-LL within 5 days of decompression and antibiotics. The patients had no sepsis related postoperative complications from the accelerated course of treatment, resulting in discharge within 2 days following URS-LL. We provide a detailed examination of each patient presentation to describe our institution's experience with treating infected kidney stones within days of urgent decompression in order to question the previous standard of treating an infected kidney stone with a more delayed intervention.
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spelling pubmed-62867502018-12-30 Early Stone Manipulation in Urinary Tract Infection Associated with Obstructing Nephrolithiasis Swonke, Megan L. Mahmoud, Ali M. Farran, Elias J. Dafashy, Tamer J. Kerr, Preston S. Kosarek, Christopher D. Sonstein, Joseph Case Rep Urol Case Report A urinary tract infection (UTI) and sepsis secondary to an obstructing stone are one of the few true urological emergencies. The accepted management of infected ureteral stones includes emergent decompression of the collecting system as well as antibiotic therapy. Despite this, no consensus guidelines clarify the optimal time to undergo definitive stone management following decompression. Historically, our institution has performed ureteroscopy with laser lithotripsy (URS-LL) treatment at least 1 to 2 weeks after decompression to allow for clinical improvement and completion of an antibiotic course. In this case series, we retrospectively review four cases in which patients had a documented UTI secondary to an obstructive ureteral stone. The patients underwent urgent decompression and, based on labs and clinical improvement, were subsequently treated with URS-LL. The presented patients received URS-LL within 5 days of decompression and antibiotics. The patients had no sepsis related postoperative complications from the accelerated course of treatment, resulting in discharge within 2 days following URS-LL. We provide a detailed examination of each patient presentation to describe our institution's experience with treating infected kidney stones within days of urgent decompression in order to question the previous standard of treating an infected kidney stone with a more delayed intervention. Hindawi 2018-11-25 /pmc/articles/PMC6286750/ /pubmed/30595937 http://dx.doi.org/10.1155/2018/2303492 Text en Copyright © 2018 Megan L. Swonke et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Swonke, Megan L.
Mahmoud, Ali M.
Farran, Elias J.
Dafashy, Tamer J.
Kerr, Preston S.
Kosarek, Christopher D.
Sonstein, Joseph
Early Stone Manipulation in Urinary Tract Infection Associated with Obstructing Nephrolithiasis
title Early Stone Manipulation in Urinary Tract Infection Associated with Obstructing Nephrolithiasis
title_full Early Stone Manipulation in Urinary Tract Infection Associated with Obstructing Nephrolithiasis
title_fullStr Early Stone Manipulation in Urinary Tract Infection Associated with Obstructing Nephrolithiasis
title_full_unstemmed Early Stone Manipulation in Urinary Tract Infection Associated with Obstructing Nephrolithiasis
title_short Early Stone Manipulation in Urinary Tract Infection Associated with Obstructing Nephrolithiasis
title_sort early stone manipulation in urinary tract infection associated with obstructing nephrolithiasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286750/
https://www.ncbi.nlm.nih.gov/pubmed/30595937
http://dx.doi.org/10.1155/2018/2303492
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