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Tryptophan Photoproduct FICZ Upregulates IL1A, IL1B, and IL6 Expression via Oxidative Stress in Keratinocytes

Ultraviolet B (UVB) irradiation activates the aryl hydrocarbon receptor (AHR), generates the reactive oxygen species (ROS), and induces the production of proinflammatory cytokines such as IL1A, IL1B, and IL6. 6-Formylindolo[3,2-b]carbazole (FICZ) is a tryptophan-derived photoproduct that is induced...

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Detalles Bibliográficos
Autores principales:	Tanaka, Yuka, Uchi, Hiroshi, Hashimoto-Hachiya, Akiko, Furue, Masutaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286782/ https://www.ncbi.nlm.nih.gov/pubmed/30595799 http://dx.doi.org/10.1155/2018/9298052

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