TGF-β induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure

The corneal endothelium (CE) dysfunction impairs optical transparency and leads to corneal allograft failure. Morphologically, CE cells are characterized by premature senescence at the late stage of corneal graft. However, the detailed molecular mechanisms are largely unknown. Here we found that tra...

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Detalles Bibliográficos
Autores principales: Li, Zhiyuan, Liu, Ting, Ma, Junwei, Guo, Qie, Ma, Liang, Lv, Qiulan, Jiang, Yan, Wei, Chao, Zhang, Jisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286827/
https://www.ncbi.nlm.nih.gov/pubmed/30482886
http://dx.doi.org/10.18632/aging.101659

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