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Aging and drug discovery

Multiple interventions in the aging process have been discovered to extend the healthspan of model organisms. Both industry and academia are therefore exploring possible transformative molecules that target aging and age-associated diseases. In this overview, we summarize the presented talks and dis...

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Autores principales: Bakula, Daniela, Aliper, Alexander M., Mamoshina, Polina, Petr, Michael A., Teklu, Amanuel, Baur, Joseph A., Campisi, Judith, Ewald, Collin Y., Georgievskaya, Anastasia, Gladyshev, Vadim N., Kovalchuk, Olga, Lamming, Dudley W., Luijsterburg, Martijn S., Martín-Montalvo, Alejandro, Maudsley, Stuart, Mkrtchyan, Garik V., Moskalev, Alexey, Olshansky, S. Jay, Ozerov, Ivan V., Pickett, Alexander, Ristow, Michael, Zhavoronkov, Alex, Scheibye-Knudsen, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286828/
https://www.ncbi.nlm.nih.gov/pubmed/30425188
http://dx.doi.org/10.18632/aging.101646
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author Bakula, Daniela
Aliper, Alexander M.
Mamoshina, Polina
Petr, Michael A.
Teklu, Amanuel
Baur, Joseph A.
Campisi, Judith
Ewald, Collin Y.
Georgievskaya, Anastasia
Gladyshev, Vadim N.
Kovalchuk, Olga
Lamming, Dudley W.
Luijsterburg, Martijn S.
Martín-Montalvo, Alejandro
Maudsley, Stuart
Mkrtchyan, Garik V.
Moskalev, Alexey
Olshansky, S. Jay
Ozerov, Ivan V.
Pickett, Alexander
Ristow, Michael
Zhavoronkov, Alex
Scheibye-Knudsen, Morten
author_facet Bakula, Daniela
Aliper, Alexander M.
Mamoshina, Polina
Petr, Michael A.
Teklu, Amanuel
Baur, Joseph A.
Campisi, Judith
Ewald, Collin Y.
Georgievskaya, Anastasia
Gladyshev, Vadim N.
Kovalchuk, Olga
Lamming, Dudley W.
Luijsterburg, Martijn S.
Martín-Montalvo, Alejandro
Maudsley, Stuart
Mkrtchyan, Garik V.
Moskalev, Alexey
Olshansky, S. Jay
Ozerov, Ivan V.
Pickett, Alexander
Ristow, Michael
Zhavoronkov, Alex
Scheibye-Knudsen, Morten
author_sort Bakula, Daniela
collection PubMed
description Multiple interventions in the aging process have been discovered to extend the healthspan of model organisms. Both industry and academia are therefore exploring possible transformative molecules that target aging and age-associated diseases. In this overview, we summarize the presented talks and discussion points of the 5th Annual Aging and Drug Discovery Forum 2018 in Basel, Switzerland. Here academia and industry came together, to discuss the latest progress and issues in aging research. The meeting covered talks about the mechanistic cause of aging, how longevity signatures may be highly conserved, emerging biomarkers of aging, possible interventions in the aging process and the use of artificial intelligence for aging research and drug discovery. Importantly, a consensus is emerging both in industry and academia, that molecules able to intervene in the aging process may contain the potential to transform both societies and healthcare.
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spelling pubmed-62868282018-12-17 Aging and drug discovery Bakula, Daniela Aliper, Alexander M. Mamoshina, Polina Petr, Michael A. Teklu, Amanuel Baur, Joseph A. Campisi, Judith Ewald, Collin Y. Georgievskaya, Anastasia Gladyshev, Vadim N. Kovalchuk, Olga Lamming, Dudley W. Luijsterburg, Martijn S. Martín-Montalvo, Alejandro Maudsley, Stuart Mkrtchyan, Garik V. Moskalev, Alexey Olshansky, S. Jay Ozerov, Ivan V. Pickett, Alexander Ristow, Michael Zhavoronkov, Alex Scheibye-Knudsen, Morten Aging (Albany NY) Meeting Report Multiple interventions in the aging process have been discovered to extend the healthspan of model organisms. Both industry and academia are therefore exploring possible transformative molecules that target aging and age-associated diseases. In this overview, we summarize the presented talks and discussion points of the 5th Annual Aging and Drug Discovery Forum 2018 in Basel, Switzerland. Here academia and industry came together, to discuss the latest progress and issues in aging research. The meeting covered talks about the mechanistic cause of aging, how longevity signatures may be highly conserved, emerging biomarkers of aging, possible interventions in the aging process and the use of artificial intelligence for aging research and drug discovery. Importantly, a consensus is emerging both in industry and academia, that molecules able to intervene in the aging process may contain the potential to transform both societies and healthcare. Impact Journals 2018-11-13 /pmc/articles/PMC6286828/ /pubmed/30425188 http://dx.doi.org/10.18632/aging.101646 Text en Copyright © 2018 Bakula et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY) 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Meeting Report
Bakula, Daniela
Aliper, Alexander M.
Mamoshina, Polina
Petr, Michael A.
Teklu, Amanuel
Baur, Joseph A.
Campisi, Judith
Ewald, Collin Y.
Georgievskaya, Anastasia
Gladyshev, Vadim N.
Kovalchuk, Olga
Lamming, Dudley W.
Luijsterburg, Martijn S.
Martín-Montalvo, Alejandro
Maudsley, Stuart
Mkrtchyan, Garik V.
Moskalev, Alexey
Olshansky, S. Jay
Ozerov, Ivan V.
Pickett, Alexander
Ristow, Michael
Zhavoronkov, Alex
Scheibye-Knudsen, Morten
Aging and drug discovery
title Aging and drug discovery
title_full Aging and drug discovery
title_fullStr Aging and drug discovery
title_full_unstemmed Aging and drug discovery
title_short Aging and drug discovery
title_sort aging and drug discovery
topic Meeting Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286828/
https://www.ncbi.nlm.nih.gov/pubmed/30425188
http://dx.doi.org/10.18632/aging.101646
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