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Aging and drug discovery
Multiple interventions in the aging process have been discovered to extend the healthspan of model organisms. Both industry and academia are therefore exploring possible transformative molecules that target aging and age-associated diseases. In this overview, we summarize the presented talks and dis...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286828/ https://www.ncbi.nlm.nih.gov/pubmed/30425188 http://dx.doi.org/10.18632/aging.101646 |
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author | Bakula, Daniela Aliper, Alexander M. Mamoshina, Polina Petr, Michael A. Teklu, Amanuel Baur, Joseph A. Campisi, Judith Ewald, Collin Y. Georgievskaya, Anastasia Gladyshev, Vadim N. Kovalchuk, Olga Lamming, Dudley W. Luijsterburg, Martijn S. Martín-Montalvo, Alejandro Maudsley, Stuart Mkrtchyan, Garik V. Moskalev, Alexey Olshansky, S. Jay Ozerov, Ivan V. Pickett, Alexander Ristow, Michael Zhavoronkov, Alex Scheibye-Knudsen, Morten |
author_facet | Bakula, Daniela Aliper, Alexander M. Mamoshina, Polina Petr, Michael A. Teklu, Amanuel Baur, Joseph A. Campisi, Judith Ewald, Collin Y. Georgievskaya, Anastasia Gladyshev, Vadim N. Kovalchuk, Olga Lamming, Dudley W. Luijsterburg, Martijn S. Martín-Montalvo, Alejandro Maudsley, Stuart Mkrtchyan, Garik V. Moskalev, Alexey Olshansky, S. Jay Ozerov, Ivan V. Pickett, Alexander Ristow, Michael Zhavoronkov, Alex Scheibye-Knudsen, Morten |
author_sort | Bakula, Daniela |
collection | PubMed |
description | Multiple interventions in the aging process have been discovered to extend the healthspan of model organisms. Both industry and academia are therefore exploring possible transformative molecules that target aging and age-associated diseases. In this overview, we summarize the presented talks and discussion points of the 5th Annual Aging and Drug Discovery Forum 2018 in Basel, Switzerland. Here academia and industry came together, to discuss the latest progress and issues in aging research. The meeting covered talks about the mechanistic cause of aging, how longevity signatures may be highly conserved, emerging biomarkers of aging, possible interventions in the aging process and the use of artificial intelligence for aging research and drug discovery. Importantly, a consensus is emerging both in industry and academia, that molecules able to intervene in the aging process may contain the potential to transform both societies and healthcare. |
format | Online Article Text |
id | pubmed-6286828 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Impact Journals |
record_format | MEDLINE/PubMed |
spelling | pubmed-62868282018-12-17 Aging and drug discovery Bakula, Daniela Aliper, Alexander M. Mamoshina, Polina Petr, Michael A. Teklu, Amanuel Baur, Joseph A. Campisi, Judith Ewald, Collin Y. Georgievskaya, Anastasia Gladyshev, Vadim N. Kovalchuk, Olga Lamming, Dudley W. Luijsterburg, Martijn S. Martín-Montalvo, Alejandro Maudsley, Stuart Mkrtchyan, Garik V. Moskalev, Alexey Olshansky, S. Jay Ozerov, Ivan V. Pickett, Alexander Ristow, Michael Zhavoronkov, Alex Scheibye-Knudsen, Morten Aging (Albany NY) Meeting Report Multiple interventions in the aging process have been discovered to extend the healthspan of model organisms. Both industry and academia are therefore exploring possible transformative molecules that target aging and age-associated diseases. In this overview, we summarize the presented talks and discussion points of the 5th Annual Aging and Drug Discovery Forum 2018 in Basel, Switzerland. Here academia and industry came together, to discuss the latest progress and issues in aging research. The meeting covered talks about the mechanistic cause of aging, how longevity signatures may be highly conserved, emerging biomarkers of aging, possible interventions in the aging process and the use of artificial intelligence for aging research and drug discovery. Importantly, a consensus is emerging both in industry and academia, that molecules able to intervene in the aging process may contain the potential to transform both societies and healthcare. Impact Journals 2018-11-13 /pmc/articles/PMC6286828/ /pubmed/30425188 http://dx.doi.org/10.18632/aging.101646 Text en Copyright © 2018 Bakula et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY) 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Meeting Report Bakula, Daniela Aliper, Alexander M. Mamoshina, Polina Petr, Michael A. Teklu, Amanuel Baur, Joseph A. Campisi, Judith Ewald, Collin Y. Georgievskaya, Anastasia Gladyshev, Vadim N. Kovalchuk, Olga Lamming, Dudley W. Luijsterburg, Martijn S. Martín-Montalvo, Alejandro Maudsley, Stuart Mkrtchyan, Garik V. Moskalev, Alexey Olshansky, S. Jay Ozerov, Ivan V. Pickett, Alexander Ristow, Michael Zhavoronkov, Alex Scheibye-Knudsen, Morten Aging and drug discovery |
title | Aging and drug discovery |
title_full | Aging and drug discovery |
title_fullStr | Aging and drug discovery |
title_full_unstemmed | Aging and drug discovery |
title_short | Aging and drug discovery |
title_sort | aging and drug discovery |
topic | Meeting Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286828/ https://www.ncbi.nlm.nih.gov/pubmed/30425188 http://dx.doi.org/10.18632/aging.101646 |
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