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Angiopoietin-1 and ανβ3 integrin peptide promote the therapeutic effects of L-serine in an amyotrophic lateral sclerosis/Parkinsonism dementia complex model

Amyotrophic lateral sclerosis (ALS) is an adult disorder of neurodegeneration that manifests as the destruction of upper and lower motor neurons. Beta-N-methylamino-L-alanine (L-BMAA), an amino acid not present in proteins, was found to cause intraneuronal protein misfolding and to induce ALS/Parkin...

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Detalles Bibliográficos
Autores principales: Cai, Hua-ying, Tian, Ke-wei, Zhang, Yuan-yuan, Jiang, Hong, Han, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286852/
https://www.ncbi.nlm.nih.gov/pubmed/30476904
http://dx.doi.org/10.18632/aging.101661