Cargando…
B Cell Siglecs–News on Signaling and Its Interplay With Ligand Binding
CD22 and Siglec-G are members of the Siglec family. Both are inhibitory co-receptors on the surface of B cells and inhibit B-cell receptor induced signaling, characterized by inhibition of the calcium mobilization and cellular activation. CD22 functions predominantly as an inhibitor on conventional...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286995/ https://www.ncbi.nlm.nih.gov/pubmed/30559744 http://dx.doi.org/10.3389/fimmu.2018.02820 |