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B Cell Siglecs–News on Signaling and Its Interplay With Ligand Binding
CD22 and Siglec-G are members of the Siglec family. Both are inhibitory co-receptors on the surface of B cells and inhibit B-cell receptor induced signaling, characterized by inhibition of the calcium mobilization and cellular activation. CD22 functions predominantly as an inhibitor on conventional...
Autores principales: | Meyer, Sarah J., Linder, Alexandra T., Brandl, Carolin, Nitschke, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286995/ https://www.ncbi.nlm.nih.gov/pubmed/30559744 http://dx.doi.org/10.3389/fimmu.2018.02820 |
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