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Tau’s Three-Repeat Domain and EFhd2 Co-incubation Leads to Increased Thioflavin Signal

Aggregation of the protein tau is a pathological hallmark of Alzheimer’s disease (AD) and related disorders. However, the molecular mechanisms that lead to tau protein aggregation are still unclear. Previously, we showed that EFhd2 protein is associated with pathological aggregated forms of tau in A...

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Detalles Bibliográficos
Autores principales: Vega, Irving E., Sutter, Alexandra, Parks, Luke, Umstead, Andrew, Ivanova, Magdalena I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286997/
https://www.ncbi.nlm.nih.gov/pubmed/30559642
http://dx.doi.org/10.3389/fnins.2018.00879