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Chronic Overexpression of Bradykinin in Kidney Causes Polyuria and Cardiac Hypertrophy
Acute intra-renal infusion of bradykinin increases diuresis and natriuresis via inhibition of vasopressin activity. However, the consequences of chronically increased bradykinin in the kidneys have not yet been studied. A new transgenic animal model producing an excess of bradykinin by proximal tubu...
Autores principales: | Barros, Carlos C., Schadock, Ines, Sihn, Gabin, Rother, Franziska, Xu, Ping, Popova, Elena, Lapidus, Irina, Plehm, Ralph, Heuser, Arnd, Todiras, Mihail, Bachmann, Sebastian, Alenina, Natalia, Araujo, Ronaldo C., Pesquero, Joao B., Bader, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287039/ https://www.ncbi.nlm.nih.gov/pubmed/30560131 http://dx.doi.org/10.3389/fmed.2018.00338 |
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