Myeloid-Specific Deletion of Mcl-1 Yields Severely Neutropenic Mice That Survive and Breed in Homozygous Form

Mouse strains with specific deficiency of given hematopoietic lineages provide invaluable tools for understanding blood cell function in health and disease. Whereas neutrophils are dominant leukocytes in humans and mice, there are no widely useful genetic models of neutrophil deficiency in mice. In...

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Detalles Bibliográficos
Autores principales: Csepregi, Janka Zsófia, Orosz, Anita, Zajta, Erik, Kása, Orsolya, Németh, Tamás, Simon, Edina, Fodor, Szabina, Csonka, Katalin, Barátki, Balázs L., Kövesdi, Dorottya, He, You-Wen, Gácser, Attila, Mócsai, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2018
Materias:
Novel Immunological Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287103/
https://www.ncbi.nlm.nih.gov/pubmed/30464050
http://dx.doi.org/10.4049/jimmunol.1701803

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