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Operationalising a conceptual framework for a contiguous hospitalisation episode to study associations between surgical timing and death after first hip fracture: a Canadian observational study

OBJECTIVE: We describe steps to operationalise a published conceptual framework for a contiguous hospitalisation episode using acute care hospital discharge abstracts. We then quantified the degree of bias induced by a first abstract episode, which does not account for hospital transfers. DESIGN: Re...

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Autores principales: Sheehan, Katie Jane, Levy, Adrian R, Sobolev, Boris, Guy, Pierre, Tang, Michael, Kuramoto, Lisa, Sutherland, Jason M, Beaupre, Lauren, Morin, Suzanne N, Harvey, Edward, Bradley, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287122/
https://www.ncbi.nlm.nih.gov/pubmed/30530471
http://dx.doi.org/10.1136/bmjopen-2017-020372
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author Sheehan, Katie Jane
Levy, Adrian R
Sobolev, Boris
Guy, Pierre
Tang, Michael
Kuramoto, Lisa
Sutherland, Jason M
Beaupre, Lauren
Morin, Suzanne N
Harvey, Edward
Bradley, Nick
author_facet Sheehan, Katie Jane
Levy, Adrian R
Sobolev, Boris
Guy, Pierre
Tang, Michael
Kuramoto, Lisa
Sutherland, Jason M
Beaupre, Lauren
Morin, Suzanne N
Harvey, Edward
Bradley, Nick
author_sort Sheehan, Katie Jane
collection PubMed
description OBJECTIVE: We describe steps to operationalise a published conceptual framework for a contiguous hospitalisation episode using acute care hospital discharge abstracts. We then quantified the degree of bias induced by a first abstract episode, which does not account for hospital transfers. DESIGN: Retrospective observational study. SETTING: All acute care hospitals in nine Canadian provinces. PARTICIPANTS: We retrieved acute hospitalisation discharge abstracts for 189 448 patients aged 65 years and older admitted to acute care with hip fracture between 2003 and 2013. PRIMARY AND SECONDARY OUTCOME MEASURES: The percentage of patients treated surgically, delayed to surgery (defined as two or more days after admission) and dying, between contiguous hospitalisation episodes and the first abstract episodes of care. RESULTS: Using contiguous hospitalisation episodes, 91.6% underwent surgery, 35.7% were delayed two or more days after admission and 6.7% died postoperatively, whereas, using the first abstract only, these percentages were 83.7%, 32.5% and 6.5%, respectively. CONCLUSION: We demonstrate that not accounting for hospital transfers when evaluating the association between surgical timing and death underestimates reporting of the percentage of patients treated surgically and delayed to surgery by 9%, and the percentage who die after surgery by 3%. Researchers must be aware of this potential and avoidable bias as, depending on the purpose of the study, erroneous inferences may be drawn.
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spelling pubmed-62871222018-12-26 Operationalising a conceptual framework for a contiguous hospitalisation episode to study associations between surgical timing and death after first hip fracture: a Canadian observational study Sheehan, Katie Jane Levy, Adrian R Sobolev, Boris Guy, Pierre Tang, Michael Kuramoto, Lisa Sutherland, Jason M Beaupre, Lauren Morin, Suzanne N Harvey, Edward Bradley, Nick BMJ Open Health Services Research OBJECTIVE: We describe steps to operationalise a published conceptual framework for a contiguous hospitalisation episode using acute care hospital discharge abstracts. We then quantified the degree of bias induced by a first abstract episode, which does not account for hospital transfers. DESIGN: Retrospective observational study. SETTING: All acute care hospitals in nine Canadian provinces. PARTICIPANTS: We retrieved acute hospitalisation discharge abstracts for 189 448 patients aged 65 years and older admitted to acute care with hip fracture between 2003 and 2013. PRIMARY AND SECONDARY OUTCOME MEASURES: The percentage of patients treated surgically, delayed to surgery (defined as two or more days after admission) and dying, between contiguous hospitalisation episodes and the first abstract episodes of care. RESULTS: Using contiguous hospitalisation episodes, 91.6% underwent surgery, 35.7% were delayed two or more days after admission and 6.7% died postoperatively, whereas, using the first abstract only, these percentages were 83.7%, 32.5% and 6.5%, respectively. CONCLUSION: We demonstrate that not accounting for hospital transfers when evaluating the association between surgical timing and death underestimates reporting of the percentage of patients treated surgically and delayed to surgery by 9%, and the percentage who die after surgery by 3%. Researchers must be aware of this potential and avoidable bias as, depending on the purpose of the study, erroneous inferences may be drawn. BMJ Publishing Group 2018-12-06 /pmc/articles/PMC6287122/ /pubmed/30530471 http://dx.doi.org/10.1136/bmjopen-2017-020372 Text en © Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Health Services Research
Sheehan, Katie Jane
Levy, Adrian R
Sobolev, Boris
Guy, Pierre
Tang, Michael
Kuramoto, Lisa
Sutherland, Jason M
Beaupre, Lauren
Morin, Suzanne N
Harvey, Edward
Bradley, Nick
Operationalising a conceptual framework for a contiguous hospitalisation episode to study associations between surgical timing and death after first hip fracture: a Canadian observational study
title Operationalising a conceptual framework for a contiguous hospitalisation episode to study associations between surgical timing and death after first hip fracture: a Canadian observational study
title_full Operationalising a conceptual framework for a contiguous hospitalisation episode to study associations between surgical timing and death after first hip fracture: a Canadian observational study
title_fullStr Operationalising a conceptual framework for a contiguous hospitalisation episode to study associations between surgical timing and death after first hip fracture: a Canadian observational study
title_full_unstemmed Operationalising a conceptual framework for a contiguous hospitalisation episode to study associations between surgical timing and death after first hip fracture: a Canadian observational study
title_short Operationalising a conceptual framework for a contiguous hospitalisation episode to study associations between surgical timing and death after first hip fracture: a Canadian observational study
title_sort operationalising a conceptual framework for a contiguous hospitalisation episode to study associations between surgical timing and death after first hip fracture: a canadian observational study
topic Health Services Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287122/
https://www.ncbi.nlm.nih.gov/pubmed/30530471
http://dx.doi.org/10.1136/bmjopen-2017-020372
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