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Three Level Thoracolumbar Spondylectomy for Recurrent Giant Cell Tumour of the Spine: A Case Report

Giant cell tumour (GCT) is a benign tumour but can be locally aggressive and with the potential to metastasise especially to the lungs. Successful treatments have been reported for long bone lesions; however, optimal surgical and medical treatment for spinal and sacral lesions are not well establish...

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Autores principales: Faruk, NA, Mohd-Amin, MZ, Awang-Ojep, DN, Teo, YY, Wong, CC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Malaysian Orthopaedic Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287132/
https://www.ncbi.nlm.nih.gov/pubmed/30555648
http://dx.doi.org/10.5704/MOJ.1811.013
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author Faruk, NA
Mohd-Amin, MZ
Awang-Ojep, DN
Teo, YY
Wong, CC
author_facet Faruk, NA
Mohd-Amin, MZ
Awang-Ojep, DN
Teo, YY
Wong, CC
author_sort Faruk, NA
collection PubMed
description Giant cell tumour (GCT) is a benign tumour but can be locally aggressive and with the potential to metastasise especially to the lungs. Successful treatments have been reported for long bone lesions; however, optimal surgical and medical treatment for spinal and sacral lesions are not well established. In treating spinal GCTs, the aim is to achieve complete tumour excision, restore spinal stability and decompress the neural tissues. The ideal surgical procedure is an en bloc spondylectomy or vertebrectomy, where all tumour cells are removed as recurrence is closely related to the extent of initial surgical excision. However, such a surgery has a high complication rate, such as dura tear and massive blood loss. We report a patient with a missed pathological fracture of T12 treated initially with a posterior subtraction osteotomy, who had recurrence three years after the index surgery and subsequently underwent a three level vertebrectomy and posterior spinal fusion.
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spelling pubmed-62871322018-12-14 Three Level Thoracolumbar Spondylectomy for Recurrent Giant Cell Tumour of the Spine: A Case Report Faruk, NA Mohd-Amin, MZ Awang-Ojep, DN Teo, YY Wong, CC Malays Orthop J Case Reports Giant cell tumour (GCT) is a benign tumour but can be locally aggressive and with the potential to metastasise especially to the lungs. Successful treatments have been reported for long bone lesions; however, optimal surgical and medical treatment for spinal and sacral lesions are not well established. In treating spinal GCTs, the aim is to achieve complete tumour excision, restore spinal stability and decompress the neural tissues. The ideal surgical procedure is an en bloc spondylectomy or vertebrectomy, where all tumour cells are removed as recurrence is closely related to the extent of initial surgical excision. However, such a surgery has a high complication rate, such as dura tear and massive blood loss. We report a patient with a missed pathological fracture of T12 treated initially with a posterior subtraction osteotomy, who had recurrence three years after the index surgery and subsequently underwent a three level vertebrectomy and posterior spinal fusion. Malaysian Orthopaedic Association 2018-11 /pmc/articles/PMC6287132/ /pubmed/30555648 http://dx.doi.org/10.5704/MOJ.1811.013 Text en © 2018 Malaysian Orthopaedic Association (MOA). All Rights Reserved http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
spellingShingle Case Reports
Faruk, NA
Mohd-Amin, MZ
Awang-Ojep, DN
Teo, YY
Wong, CC
Three Level Thoracolumbar Spondylectomy for Recurrent Giant Cell Tumour of the Spine: A Case Report
title Three Level Thoracolumbar Spondylectomy for Recurrent Giant Cell Tumour of the Spine: A Case Report
title_full Three Level Thoracolumbar Spondylectomy for Recurrent Giant Cell Tumour of the Spine: A Case Report
title_fullStr Three Level Thoracolumbar Spondylectomy for Recurrent Giant Cell Tumour of the Spine: A Case Report
title_full_unstemmed Three Level Thoracolumbar Spondylectomy for Recurrent Giant Cell Tumour of the Spine: A Case Report
title_short Three Level Thoracolumbar Spondylectomy for Recurrent Giant Cell Tumour of the Spine: A Case Report
title_sort three level thoracolumbar spondylectomy for recurrent giant cell tumour of the spine: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287132/
https://www.ncbi.nlm.nih.gov/pubmed/30555648
http://dx.doi.org/10.5704/MOJ.1811.013
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