The TGF-β1 Signaling Pathway as an Attractive Target in the Fibrosis Pathogenesis of Sjögren's Syndrome

Transforming growth factor β1 (TGF-β1) plays a crucial role in the induction of fibrosis, often associated with chronic phases of inflammatory diseases contributing to marked fibrotic changes that compromise normal organ function. The TGF-β1 signal exerts its biological effects via the TGF-β/SMAD/Sn...

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Detalles Bibliográficos
Autores principales: Sisto, Margherita, Lorusso, Loredana, Ingravallo, Giuseppe, Tamma, Roberto, Ribatti, Domenico, Lisi, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287147/
https://www.ncbi.nlm.nih.gov/pubmed/30598637
http://dx.doi.org/10.1155/2018/1965935

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