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Establishment of quality function deployment with special reference to good manufacturing practice of Chandraprabha Vati

CONTEXT: Quality function deployment (QFD) is a powerful tool for the translation of vague, imprecise customer requirements into clear, measurable technical requirements. AIMS: The objective of this article is twofold: (a) to propose a platform conceptual model for Chandraprabha Vati and (b) to pres...

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Autores principales: Gandhi, Abhay Jayprakash, Shukla, Vinay J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt. Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287407/
https://www.ncbi.nlm.nih.gov/pubmed/30595632
http://dx.doi.org/10.4103/ayu.AYU_44_18
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author Gandhi, Abhay Jayprakash
Shukla, Vinay J.
author_facet Gandhi, Abhay Jayprakash
Shukla, Vinay J.
author_sort Gandhi, Abhay Jayprakash
collection PubMed
description CONTEXT: Quality function deployment (QFD) is a powerful tool for the translation of vague, imprecise customer requirements into clear, measurable technical requirements. AIMS: The objective of this article is twofold: (a) to propose a platform conceptual model for Chandraprabha Vati and (b) to present 10-step procedure to build QFD matrix. MATERIALS AND METHODS: The method deals with, first, preparing two conceptual models for Chandraprabha Vati for the sake of manufacturing unit. The survey study was carried out for two products for the selection of customer requirement. Then, with the help of survey study QFD’s house of quality matrix was prepared which contained two products, i.e., classical product prepared by pharmacy of university and marketed product. High performance thin layer chromatography study was also carried out. STATISTICAL ANALYSIS USED: Principal component analysis (PCA) was applied to the data using unscrambler software. RESULTS: The results of QFD chart and PCA analysis were obtained from the two surveys. The first survey reveals that if proper care is taken during preparation on hardness and capping of Vati, then product goes toward zero defects. The second survey reveals that if proper care is taken during preparation on hardness, capping and sticking, then physically Vati goes toward zero defects. CONCLUSIONS: The 10-step procedure facilitates the process of reasoning and reduces the time spent for manufacturing with zero defect in product.
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spelling pubmed-62874072018-12-28 Establishment of quality function deployment with special reference to good manufacturing practice of Chandraprabha Vati Gandhi, Abhay Jayprakash Shukla, Vinay J. Ayu Pharmaceutical Study CONTEXT: Quality function deployment (QFD) is a powerful tool for the translation of vague, imprecise customer requirements into clear, measurable technical requirements. AIMS: The objective of this article is twofold: (a) to propose a platform conceptual model for Chandraprabha Vati and (b) to present 10-step procedure to build QFD matrix. MATERIALS AND METHODS: The method deals with, first, preparing two conceptual models for Chandraprabha Vati for the sake of manufacturing unit. The survey study was carried out for two products for the selection of customer requirement. Then, with the help of survey study QFD’s house of quality matrix was prepared which contained two products, i.e., classical product prepared by pharmacy of university and marketed product. High performance thin layer chromatography study was also carried out. STATISTICAL ANALYSIS USED: Principal component analysis (PCA) was applied to the data using unscrambler software. RESULTS: The results of QFD chart and PCA analysis were obtained from the two surveys. The first survey reveals that if proper care is taken during preparation on hardness and capping of Vati, then product goes toward zero defects. The second survey reveals that if proper care is taken during preparation on hardness, capping and sticking, then physically Vati goes toward zero defects. CONCLUSIONS: The 10-step procedure facilitates the process of reasoning and reduces the time spent for manufacturing with zero defect in product. Medknow Publications & Media Pvt. Ltd. 2018 /pmc/articles/PMC6287407/ /pubmed/30595632 http://dx.doi.org/10.4103/ayu.AYU_44_18 Text en Copyright: © 2018 AYU (An International Quarterly Journal of Research in Ayurveda) http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Pharmaceutical Study
Gandhi, Abhay Jayprakash
Shukla, Vinay J.
Establishment of quality function deployment with special reference to good manufacturing practice of Chandraprabha Vati
title Establishment of quality function deployment with special reference to good manufacturing practice of Chandraprabha Vati
title_full Establishment of quality function deployment with special reference to good manufacturing practice of Chandraprabha Vati
title_fullStr Establishment of quality function deployment with special reference to good manufacturing practice of Chandraprabha Vati
title_full_unstemmed Establishment of quality function deployment with special reference to good manufacturing practice of Chandraprabha Vati
title_short Establishment of quality function deployment with special reference to good manufacturing practice of Chandraprabha Vati
title_sort establishment of quality function deployment with special reference to good manufacturing practice of chandraprabha vati
topic Pharmaceutical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287407/
https://www.ncbi.nlm.nih.gov/pubmed/30595632
http://dx.doi.org/10.4103/ayu.AYU_44_18
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