Synthesis of small peptide compounds, molecular docking, and inhibitory activity evaluation against phosphatases PTP1B and SHP2

BACKGROUND: The protein tyrosine phosphatases PTP1B and SHP2 are promising drug targets in treatment design for breast cancer. Searching for specific inhibitors of their activity has recently become the challenge of many studies. Previous work has indicated that the promising PTP inhibitors may be s...

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Detalles Bibliográficos
Autores principales: Kostrzewa, Tomasz, Sahu, Kamlesh K, Gorska-Ponikowska, Magdalena, Tuszynski, Jack A, Kuban-Jankowska, Alicja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287413/
https://www.ncbi.nlm.nih.gov/pubmed/30584278
http://dx.doi.org/10.2147/DDDT.S186614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287413/
https://www.ncbi.nlm.nih.gov/pubmed/30584278
http://dx.doi.org/10.2147/DDDT.S186614

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