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Clinical benefit from afatinib in an advanced squamous cell lung carcinoma patient harboring HER2 S310Y mutation: a case report
BACKGROUND: HER2 mutations are identified in approximately 2% of non-small-cell lung cancer (NSCLC) cases and are predominantly observed in non-smokers, females, and adenocarcinoma patients. Although afatinib is recommended for treating NSCLC patients with HER2 mutation, the therapy is most efficaci...
Autores principales: | Gao, Yan, Zheng, Aihong, Zhu, Xiuming, Song, Jia, Xue, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287414/ https://www.ncbi.nlm.nih.gov/pubmed/30584328 http://dx.doi.org/10.2147/OTT.S182812 |
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